|
Valsartan
API |
|
|
|
Haorui supplies high quality Valsartan API produced by our
GMP facility that has been successfully inspected by the
FDA.
We offer
competitive prices and support our products with reliable technical and
regulatory services. Valsartan API is available from R&D to
commercial quantities. Please contact us for more details. |
| |
|
The following
information is provided for general information purposes
ONLY. |
|
|
|
What is Valsartan?
|
|
Valsartan is a nonpeptide, orally active, and specific angiotensin II antagonist acting on
theAT1 receptor subtype.
Valsartan is a white
to practically white
fine powder. It is soluble
in ethanol and methanol and slightly soluble in water.
|
|
|
|
How does Valsartan work?
|
|
Valsartan
is used alone or in combination with other
medications to treat high blood pressure. It is also
used to treat heart failure in people who cannot
take angiotensin-converting enzyme (ACE) inhibitors.
Valsartan is in a class of medications called
angiotensin II receptor antagonists. It works by
blocking the action of certain chemicals that
tighten the blood vessels, so blood flows more
smoothly.
|
|
|
|
Valsartan
mode of action
|
|
Valsartan
is available as tablets for oral
administration, containing 40 mg, 80 mg, 160 mg or 320 mg of valsartan. The inactive ingredients
of the tablets are colloidal silicon dioxide,
crospovidone, hydroxypropyl methylcellulose, iron oxides (yellow, black and/or red), magnesium stearate, microcrystalline
cellulose, polyethylene
glycol 8000, and titanium dioxide.
|
|
|
|
Valsartan
comes as a tablet to take by mouth. For the
treatment of high blood pressure, it is usually
taken once a day with or without food. For the
treatment of heart failure, it is usually taken
twice a day with or without food.To help you
remember to take valsartan, take it around the same
time every day. Follow the directions on your
prescription label carefully, and ask your doctor or
pharmacist to explain any part you do not
understand. Take valsartan exactly as directed. Do
not take more or less of it or take it more often
than prescribed by your doctor.
|
|
|
Valsartan
pharmacokinetics
|
|
Valsartan
is chemically described as
N-(1-oxopentyl)-N-[[2′-(1H-tetrazol-5-yl)
[1,1′- biphenyl]-4-yl]methyl]-L-valine. Its empirical formula is C24H29N5O3,
its molecular weight
is 435.5, and its structural
formula is
|
|
|
|
Valsartan
side effects
|
|
Valsartan
may cause side effects. Tell your doctor if any of
these symptoms are severe or do not go away:
 |
dizziness
|
|
headache
|
|
excessive
tiredness
|
|
diarrhea
|
|
stomach
pain
|
|
back
pain
|
|
joint
pain
|
|
|
|
|
Some
side effects can be serious. The following symptoms
are uncommon, but if you experience any of them,
call your doctor immediately:
|
swelling
of the face, throat, tongue, lips, eyes, hands,
feet, ankles, or lower legs
|
|
hoarseness
|
|
difficulty
breathing or swallowing
|
|
fainting
|
|
|
|
|
Disclaimer:
|
|
Information on
this page is provided for general information
purposes. You should not make a clinical treatment
decision based on information contained in this page
without consulting other references including the
package insert of the drug, textbooks and where
relevant, expert opinion. We cannot be held
responsible for any errors you make in administering
drugs mentioned on this page, nor for use of any
erroneous information contained on this page.
|
|
|
