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Sorafenib Tosylate
API |
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Haorui supplies high quality Sorafenib Tosylate API produced by our
GMP facility that has been successfully inspected by the
FDA.
We offer
competitive prices and support our products with reliable technical and
regulatory services. Sorafenib Tosylate API is available from R&D to
commercial quantities. Please contact us for more details. |
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The following
information is provided for general information purposes
ONLY. |
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What is Sorafenib Tosylate? |
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Sorafenib is used to treat advanced renal
cell carcinoma (a type of cancer that begins in the
kidneys). Sorafenib is in a class of medications called
multikinase inhibitors. It works by slowing the spread of
cancer cells. |
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How should
Sorafenib Tosylate be used? |
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Sorafenib comes as a tablet to take by
mouth. It is usually taken twice a day. Sorafenib is taken
without food, one hour before or 2 hours after a meal. Take
sorafenib at around the same times every day. Follow the
directions on your prescription label carefully, and ask
your doctor or pharmacist to explain any part you do not
understand. Take sorafenib exactly as directed. Do not take
more or less of it or take it more often than prescribed by
your doctor.
Swallow the tablets whole with water. Do
not split, chew, or crush them.
Your doctor may decrease your dose of
sorafenib during your treatment, or may tell you to stop
taking sorafenib for a period of time if you experience side
effects. Be sure to tell your doctor how you are feeling
during your treatment with sorafenib.
Continue to take sorafenib even if you
feel well. Do not stop taking sorafenib without talking to
your doctor.
Ask your pharmacist or doctor for a copy
of the manufacturer's information for the patient. |
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Other uses for
Sorafenib Tosylate |
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Sorafenib Tosylate may be prescribed for other uses; ask your
doctor or pharmacist for more information. |
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What special precautions should I follow?
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Before taking sorafenib,
-tell your doctor
and pharmacist if you are allergic to sorafenib or any
other medications.
-tell your doctor
and pharmacist what prescription and nonprescription
medications, vitamins, and nutritional supplements you are
taking or plan to take. Be sure to mention any of the
following: anticoagulants (blood thinners) such as
warfarin (Coumadin), bupropion (Wellbutrin, Zyban),
carbamazepine (Equetro, Tegretol), cyclophosphamide (Cytoxan,
Neosar), dexamethasone, doxorubicin (Doxil, Adriamycin),
efavirenz (Sustiva), ifosfamide, irinotecan (Camptosar),
methadone (Dolophine, Methadose), phenobarbital, phenytoin
(Dilantin, Phenytek), or rifampin (Rifadin, Rimactane).
Your doctor may need to change the doses of your
medications or monitor you carefully for side effects.
-tell your doctor
what herbal products you are taking, especially St. John's
wort.
-tell your doctor
if you have or have ever had high blood pressure, bleeding
problems, chest pain, a heart attack, kidney disease other
than kidney cancer, or heart or liver disease.
-you should know
that sorafenib may decrease fertility in men and women.
However, you should not assume that you or your partner
cannot become pregnant. If you are pregnant or
breastfeeding, you should tell your doctor before you
begin taking this drug. Use a reliable method of birth
control during your treatment and for 2 weeks after you
stop taking sorafenib. Talk to your doctor about birth
control methods that will work for you. Sorafenib may harm
the fetus.
-if you are
having surgery, including dental surgery, tell the doctor
or dentist that you are taking sorafenib.
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What side effects can
Sorafenib Tosylate
cause? |
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Sorafenib may cause side effects. Tell
your doctor if any of these symptoms are severe or do not go
away:
-tiredness
-weakness
-rash
-skin redness
-hair loss
-itching
-dry skin
-nausea
-vomiting
-loss of appetite
-constipation
-diarrhea
-stomach pain
-dry mouth
-mouth sores
-weight loss
-joint pain
-numbness, pain
or tingling in hands or feet
-headache
Some side effects can be serious. If you
experience any of these symptoms, call your doctor
immediately:
-unusual bruising
or bleeding
-black and/or
tarry stools
-red blood in
stools
-bloody vomit
-vomiting
material that looks like coffee grounds
-severe abdominal
pain
-chest pain
-shortness of
breath
-sudden severe
headache
-confusion
-changes in
vision
-seizures
-redness, pain,
swelling or blisters on the palms of the hands or soles of
the feet
Sorafenib may cause other side effects.
Call your doctor if you have any unusual problems while
taking this medication. |
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What storage conditions are needed for
Sorafenib Tosylate? |
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Keep this medication in the container it came in, tightly
closed, and out of reach of children. Store it at room
temperature and away from excess heat and moisture (not in
the bathroom). Throw away any medication that is outdated or
no longer needed. Talk to your pharmacist about the proper
disposal of your medication. |
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In case of emergency/overdose |
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In case of overdose, call your local
poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services
at 911.
Symptoms of overdose may include:
-diarrhea
-rash or other skin problems
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What other information should I know? |
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Keep all appointments with your doctor.
Your doctor will check your blood pressure every week during
the first six weeks of your treatment and then from time to
time as needed.
Do not let anyone else take your
medication. Ask your pharmacist any questions you have about
refilling your prescription. |
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Disclaimer:
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Information on
this page is provided for general information
purposes. You should not make a clinical treatment
decision based on information contained in this page
without consulting other references including the
package insert of the drug, textbooks and where
relevant, expert opinion. We cannot be held
responsible for any errors you make in administering
drugs mentioned on this page, nor for use of any
erroneous information contained on this page.
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