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Pemetrexed disodium
API |
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Haorui supplies high quality Pemetrexed disodium API produced by our
GMP facility that has been successfully inspected by the
FDA.
We offer
competitive prices and support our products with reliable technical and
regulatory services. Pemetrexed disodium API is available from R&D to
commercial quantities. Please contact us for more details. |
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The following
information is provided for general information purposes
ONLY. |
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What is Pemetrexed disodium? |
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Pemetrexed is used with another chemotherapy
(anti-cancer) medication to treat malignant pleural
mesothelioma (a type of cancer that affects the inside
lining of the chest cavity). Pemetrexed is also used to
treat non-small cell lung cancer. Pemetrexed is in a class
of medications called antifolate antineoplastic agents. It
works by blocking the action of a certain substance in the
body that may help cancer cells multiply. |
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How should
Pemetrexed disodium be
used? |
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Pemetrexed comes as a solution (liquid)
to be injected into a vein. Pemetrexed is administered by a
doctor or nurse in a medical office or infusion center. It
is usually given once every 21 days.
Your doctor will probably tell you to
take other medications, such as folic acid (a vitamin),
vitamin B12, and a corticosteroid such as
dexamethasone (Decadron) to decrease some of the side
effects of this medication. Your doctor will give you
directions for taking these medications. Follow your
doctor's directions carefully. Ask your doctor or pharmacist
to explain any part you do not understand. If you miss a
dose of one of these medications, call your doctor.
Your doctor will ask you to have regular
blood tests before and during treatment with pemetrexed.
Your doctor may change your dose of pemetrexed or delay
treatment based on the results of the blood tests.
Ask your pharmacist or doctor for a copy
of the manufacturer's information for the patient. |
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Other uses for
Pemetrexed disodium
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Pemetrexed disodium may
be prescribed for other uses; ask your doctor or pharmacist
for more information. |
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What special precautions should I follow? |
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Before taking pemetrexed,
 | tell your doctor and pharmacist if you are allergic to
pemetrexed, mannitol,or any other medications.
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| tell your doctor and pharmacist what other
prescription and nonprescription medications, vitamins,
nutritional supplements, and herbal products you are
taking or plan to take. Be sure to mention any of the
following: aspirin and other nonsteroidal
anti-inflammatory medications (NSAIDs) such as ibuprofen
(Advil, Motrin) and naproxen (Aleve, Naprosyn), or
probenecid. Your doctor may need to change the doses of
your medications or monitor you carefully for side
effects. |
| tell your doctor if you have a pleural effusion
(excess fluid between the linings around the lung),
ascites (excess fluid in the abdomen); or have or have
ever had kidney or liver disease. |
| tell your doctor if you are pregnant or plan to become
pregnant. You should use birth control to prevent
pregnancy during your treatment with pemetrexed. If you
become pregnant while using this medication, call your
doctor. Pemetrexed may harm the fetus. |
| tell your doctor if you are breast-feeding. You should
not breast-feed during your treatment with pemetrexed.
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What special dietary instructions should I
follow? |
| Unless your doctor tells you otherwise, continue your normal
diet. |
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What should I do if I forget a dose? |
| If you miss an appointment to receive a dose of pemetrexed,
call your doctor as soon as possible. |
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What side effects can
Pemetrexed disodium cause? |
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Pemetrexed may cause side effects. Tell
your doctor if any of these symptoms are severe or do not go
away:
| nausea
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| vomiting
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| constipation
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| loss of appetite
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| weight loss
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| tiredness
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| weakness
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| pale skin
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| headache
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| dizziness
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| confusion
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| fast heartbeat
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| difficulty falling asleep or staying asleep
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| changes in mood
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| depression
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| joint or muscle pain
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Some side effects can be serious. If you
experience any of these symptoms, call your doctor
immediately:
| diarrhea
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| sores and/or redness in the mouth or throat or on the
lips |
| unusual bleeding or bruising
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| sore throat, fever, chills, cough or other signs of
infection |
| chest pain
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| difficulty breathing or swallowing
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| slow or difficult speech
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| dizziness or faintness
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| weakness or numbness of an arm or leg
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| pain, burning, numbness, or tingling in the hands or
feet |
| hives
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| rash
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| itching
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| decreased urination
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Pemetrexed may cause other side effects.
Call your doctor if you have any unusual problems while
taking this medication. |
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In case of emergency/overdose |
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In case of overdose, call your local
poison control center at 1-800-222-1222. If the victim has
collapsed or is not breathing, call local emergency services
at 911.
Symptoms of overdose may include:
| rash
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| sores and/or redness in the mouth or throat or on the
lips |
| unusual bleeding or bruising
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| sore throat, fever, chills, cough or other signs of
infection |
| extreme tiredness
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| weakness
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| pale skin
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| headache
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| dizziness
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| confusion
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| fast heartbeat
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| difficulty falling asleep or staying asleep
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What other information should I know?
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| Keep all appointments with your doctor and the laboratory.
Your doctor will order certain lab tests to check your
body's response to pemetrexed. |
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Disclaimer:
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Information on
this page is provided for general information
purposes. You should not make a clinical treatment
decision based on information contained in this page
without consulting other references including the
package insert of the drug, textbooks and where
relevant, expert opinion. We cannot be held
responsible for any errors you make in administering
drugs mentioned on this page, nor for use of any
erroneous information contained on this page.
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