Nabumetone

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Nabumetone API

 

Haorui supplies high quality Nabumetone API produced by our GMP facility that has been successfully inspected by the FDA. We offer competitive prices and support our products with reliable technical and regulatory services.  Nabumetone API is available from R&D to commercial quantities. Please contact us for more details.

 

The following information is provided for general information purposes ONLY.

 

What is Nabumetone?

Nabumetone is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by osteoarthritis and rheumatoid arthritis. Nabumetone is in a class of medications called nonsteroidal anti-inflammatory medications (NSAIDs). It works by stopping the body's production of a substance that causes pain, fever, and inflammation.

 

The history of Nabumetone

Nabumetone is a white to off-white crystalline substance with a molecular weight of 228.3. It is nonacidic and practically insoluble in water, but soluble in alcohol and most organic solvents. It has an n-octanol:phosphate buffer partition coefficient of 2400 at pH 7.4.

 

Nabumetone mode of action

Nabumetone comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food. To help you remember to take nabumetone, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nabumetone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Nabumetone pharmacokinetics

Each oval-shaped, film-coated tablet contains 500 mg or 750 mg of nabumetone. Inactive ingredients consist of hydroxypropyl methylcellulose, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium lauryl sulfate, sodium starch glycolate and titanium dioxide. The 750 mg tablets also contain iron oxides.

 

Nabumetone side effects

Nabumetone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

-diarrhea

-heartburn

-stomach pain

-constipation

-gas or bloating

-upset stomach

-dizziness

-headache

-dry mouth

-white patches in the mouth

-vomiting

-excessive tiredness

-nervousness

-increased sweating

-difficulty falling asleep or staying asleep

 

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.    

 

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