Mestranol

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Mestranol API

 

Haorui supplies high quality Mestranol API produced by our GMP facility that has been successfully inspected by the FDA. We offer competitive prices and support our products with reliable technical and regulatory services.  Mestranol API is available from R&D to commercial quantities. Please contact us for more details.

 

  The following information is provided for general information purposes ONLY.

 

What is Mestranol?

A synthetic estrogen, C21H26O2, used in combination with a progestin in oral contraceptive preparations.

 MESTRANOL products are effective as oral contraceptives (birth control pills or 'the pill'). These products combine natural or synthetic estrogens and progestins, similar to the natural sex hormones (estrogen and progesterone) produced in a woman's body. Mestranol is an estrogen and norethindrone is a progestin. These products can prevent ovulation and pregnancy. In general, a combination of estrogen and progestin works better than a single-ingredient product. Mestranol/norethindrone tablets can also help regulate menstrual flow, treat acne, or may be used for other hormone related problems in females. On rare occasions, they may be prescribed for other purposes. The type and amount of estrogen and/or progestin may be different from one product to another. For some formulations, a generic product is available

 

Mestranol mode of action

What should my health care professional know before I use mestranol; norethindrone?
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blood clots

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blood sugar problems, like diabetes

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cancer of the breast, cervix, ovary, uterus, vagina, or unusual vaginal bleeding that has not been evaluated by a health care professional

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depression

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fibroids

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gallbladder disease

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heart or circulation problems

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high blood pressure

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jaundice

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liver disease

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menstrual problems

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migraine headaches

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tobacco smoker

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stroke

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an unusual or allergic reaction to estrogen/progestin, other hormones, medicines, foods, dyes, or preservatives

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pregnant or trying to get pregnant, breast-feeding

Take mestranol pills by mouth. Before you start taking these pills decide what is a suitable time of day and always take them at the same time of day and in the order directed. Swallow the pills with a drink of water. Take with food to reduce stomach upset. Do not take more often than directed

 Most products contain a 21-day supply of pills containing the active ingredients. Some products contain an additional 7 pills containing iron or inactive ingredients to be taken during the week of menstruation; this reduces the chance of missing the first day of the next cycle. Most products are to be started on the first Sunday after you start your period or on the first day of your period. You may need to ask your health care provider which day you should start your packet

 

Mestranol side effects

The following symptoms or side effects may be related to blood clots and require immediate medical or emergency help:

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chest pain

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coughing up blood

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dizziness or fainting spells

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leg, arm or groin pain

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severe or sudden headaches

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stomach pain (severe)

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sudden shortness of breath

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sudden loss of coordination, especially on one side of the body

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swelling of the hands, feet or ankles, or rapid weight gain

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vision or speech problems

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weakness or numbness in the arms or legs, especially on one side of the body

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Other serious side effects are rare. Contact your health care provider as soon as you can if the following side effects occur:

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breast tissue changes or discharge

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changes in vaginal bleeding during your period or between your periods

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headaches or migraines

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increases in blood sugar, especially if you have diabetes

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increases in blood pressure, especially if you are known to have high blood pressure

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symptoms of vaginal infection (itching, irritation or unusual discharge)

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tenderness in the upper abdomen

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vomiting

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yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your health care provider if they continue or are bothersome):

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breakthrough bleeding and spotting that continues beyond the 3 initial cycles of pills

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breast tenderness

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mild stomach upset

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mood changes, anxiety, depression, frustration, anger, or emotional outbursts

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increased or decreased appetite

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increased sensitivity to sun or ultraviolet light

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nausea

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skin rash, acne, or brown spots on the skin

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tiredness

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weight gain

 

What if I miss a dose?

Try not to miss a dose. If you do, it may be necessary to consult your prescriber or health care professional. The following information describes only some of the ways that missed doses can be handled.

21-day schedule: If you miss one dose, take it as soon as you remember and then take the next pill at the regular time as usual. You may take 2 tablets in one day. If you miss two doses (days) in a row, take 2 tablets for the next 2 days, then, continue with your regular schedule. Whenever 1 or 2 doses are missed, you should use a second method of contraception for the next 7 days in addition to taking the pills. If you miss three doses in a row, you should notify your physician or other health care professional for instructions. You will probably need to throw away the rest of the tablets in that cycle pack and start over. Another method of contraception should be used until at least 7 doses have been taken in the new cycle. Missing a pill can cause spotting or light bleeding. Make sure that no more than 7 days pass at the end of the 21 day cycle, before you start your next pack of pills

 

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.    

 

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