Ibandronate API

Haorui supplies high quality Ibandronate API produced by our GMP facility that has been successfully inspected by the FDA. We offer competitive prices and support our products with reliable technical and regulatory services.  Ibandronate API is available from R&D to commercial quantities. Please contact us for more details.

The following information is provided for general information purposes ONLY.

What is Ibandronate sodium?

Ibandronate sodium is a bisphosphonate medication. It is not a hormone. Ibandronate sodium works only on the bone and does not affect the heart, breast, uterus or other parts of the body.

How does Ibandronate sodium work?

Healthy bones are continuously remodeled (broken down and then reformed); the minerals and other components of bones are reabsorbed by one set of cells (osteoclasts) and replaced by another set of cells to form new bone. Ibandronate suppresses the activity of osteoclasts; consequently, the breakdown of bone tissue occurs more slowly than the laying down of new bone. As a result, bone density and strength are preserved.

Clinical studies indicate that Ibandronate sodium increases bone mineral density of the existing skeleton and reduces the risk of spine fractures for postmenopausal women with osteoporosis. In postmenopausal women with very severe osteoporosis, Ibandronate sodium reduces the risk of fractures throughout the skeleton. Like all medications, it is important to discuss all of the potential benefits and risks of taking this medication with your medical professional.

Ibandronate sodium Drug Interaction

Aluminum-, Calcium-, or magnesium-containing antacids, if needed, should be taken no sooner than 1 hour after taking Ibandronate.

Ibandronate sodium Disease Interactions

Kidney impairment or a gastrointestinal disease may increase the risk of side effects. Low blood Calcium levels and vitamin D deficiency must be treated before using ibandronate.

Ibandronate sodium side effects

The common side effects of Ibandronate sodium may include upset stomach, pain in the extremities (arms or legs) and diarrhea. Ibandronate sodium may also cause ulcers in the stomach or esophagus (the tube that connects your mouth and stomach), heartburn (esophagitis), or difficult/painful swallowing (dysphagia). Heartburn and irritation of the esophagus but can usually be avoided by taking the medication properly. Do not take Ibandronate sodium with any other beverages such as mineral water, juice, milk, coffee or tea.

Ibandronate sodium has the potential adverse effect of flu-like symptoms (that may last for a few days) and rarely, dental complications that occur mostly in high risk patients. 

Ibandronate sodium Special Conditions To Observe

Pregnancy---Consult your doctor about whether the benefits of taking the medicine outweigh the potential risks to the unborn child.

Breast feeding---Ibandronate may pass into breast milk; caution is advised. Consult your doctor for specific advice.

If you take a much larger dose than prescribed, call your doctor, emergency medical services (EMS), or a poison control center.

Ibandronate sodium should be Stored in a tightly sealed container away from heat, moisture, and direct light.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.