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Gefitinib
API |
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Haorui supplies high quality Gefitinib API produced by our
GMP facility that has been successfully inspected by the
FDA.
We offer competitive prices and support our products with reliable technical and
regulatory services. Gefitinib API is available from R&D to
commercial quantities. Please contact us for more details. |
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The following
information is provided for general information purposes
ONLY. |
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What is Gefitinib? |
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Gefitinib is used to treat non-small cell
lung cancer in people who have already been treated with
certain other chemotherapy medications and have not improved
or whose condition has worsened. Gefitinib has not been
shown to help people who have non-small cell lung cancer
live longer. There are other medications that may help
people who have non-small cell lung cancer live longer.
Therefore, only people who have already taken gefitinib and
benefited from the medication should continue to take it.
People who have never taken gefitinib should start their
treatment with a medication that is known to help patients
with lung cancer live longer. Gefitinib is in a class of
anti-cancer medications called epidermal growth factor
receptor (EGFR) tyrosine kinase inhibitors. It works by
blocking the action of a certain naturally occurring
substance that may be needed to help cancer cells multiply. |
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How should Gefitinib be used? |
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Gefitinib comes as a tablet to take by
mouth. It is usually taken with or without food once a day.
Take gefitinib at around the same time every day. Follow the
directions on your prescription label carefully, and ask
your doctor or pharmacist to explain any part you do not
understand. Take gefitinib exactly as directed. Do not take
more or less of it or take it more often than prescribed by
your doctor.
If you are unable to swallow the
tablets, you may dissolve them in water. Place one tablet in
a half a glass of plain, non-carbonated drinking water. Stir
with a spoon for about 10 minutes until the tablet is
dissolved. Do not use the spoon to crush the tablet. Drink
the mixture right away. Rinse the glass with another half
glass of water and drink the rinse water to be sure that you
swallow all of the medication.
Gefitinib is not available in
pharmacies. You can only get gefitinib through a
distribution program that has been set up by the
manufacturer for people who have taken gefitinib in the
past. You will need to sign a consent form before you
receive any medication. You will receive your medication by
mail from a specific mail order pharmacy. Ask your doctor if
you have any questions about receiving your medication. |
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Other uses for Gefitinib |
| Gefitinib may be prescribed for other uses; ask your doctor
or pharmacist for more information. |
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What special precautions should I follow? |
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Before taking gefitinib,
 | tell your doctor and pharmacist if you are allergic to
gefitinib or any other medications. |
| tell your doctor and pharmacist what prescription and
nonprescription medications, vitamins, and nutritional
supplements you are taking or plan to take. Be sure to
mention any of the following: anticoagulants ('blood
thinners') such as warfarin (Coumadin); antifungals such
as itraconazole (Sporanox), ketoconazole (Nizoral), and
voriconazole (Vfend); carbamazepine (Carbatrol, Equetro,
Tegretol); amiodarone (Cordarone, Pacerone);
clarithromycin (Biaxin); diltiazem (Cardizem, Dilacor,
Tiazac); erythromycin (E.E.S, E-Mycin, Erythrocin);
fluvoxamine (Luvox); medications for heartburn and ulcers
such as cimetidine (Tagamet), famotidine (Pepcid),
nizatidine (Axid), and ranitidine (Zantac); metoprolol (Lopressor,
Toprol XL); rifabutin (Mycobutin); rifampin (Rifadin,
Rimactane); medications for human immunodeficiency virus
(HIV) such as indinavir (Crixivan), nelfinavir (Viracept),
and ritonavir (Norvir, in Kaletra); nefazodone;
phenobarbital; phenytoin (Dilantin); verapamil (Calan,
Covera, Isoptin, Verelan); and vinorelbine (Navelbine).
Many other medications may interact with gefitinib, so be
sure to tell your doctor about all the medications you are
taking, even those that do not appear on this list. Your
doctor may need to change the doses of your medications or
monitor you carefully for side effects. |
| tell your doctor what herbal products you are taking,
especially St. John's wort. |
| tell your doctor if you have or have ever had
pulmonary fibrosis (scarring of the lungs), or liver or
kidney disease. |
| tell your doctor if you are pregnant or plan to become
pregnant. You should use birth control to prevent
pregnancy during your treatment with gefitinib and for
some time after you stop using the medication. If you
become pregnant while taking gefitinib, call your doctor.
Gefitinib may harm the fetus and increase the risk of
pregnancy loss. |
| tell your doctor if you are breast-feeding. You should
not breast-feed while you are taking gefitinib.
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What side effects can Gefitinib cause? |
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Gefitinib may cause side effects. Tell
your doctor if any of these symptoms are severe or do not go
away:
| dry skin
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| itching
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| rash
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| acne
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| mouth sores
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| weight loss
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| weakness
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Some side effects can be serious. If you
experience any of these symptoms, call your doctor
immediately:
| new or worsening shortness of breath, cough, or fever
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| diarrhea
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| nausea
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| vomiting
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| loss of appetite
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| eye pain, redness, or irritation
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| change in vision
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| growth of eyelashes on the inside of the eyelid
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| hives
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| swelling of the eyes, face, lips, tongue, throat,
hands, arms, feet, ankles or lower legs |
Gefitinib may cause other side effects.
Call your doctor if you have any unusual problems while
taking this medication. |
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What storage conditions are needed for
Gefitinib? |
| Keep Gefitinib in the container it came in, tightly closed,
and out of reach of children. Store it at room temperature
and away from excess heat and moisture (not in the
bathroom). Throw away any medication that is outdated or no
longer needed. Talk to your pharmacist about the proper
disposal of your medication. |
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What other information should I know? |
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Keep all appointments with your doctor
and the laboratory. Your doctor will order certain lab tests
to check your body's response to gefitinib.
Do not let anyone else take your
medication. Ask your pharmacist any questions you have about
refilling your prescription. |
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Disclaimer:
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Information on this page is provided for
general information purposes. You should not make a clinical
treatment decision based on information contained in this
page without consulting other references including the
package insert of the drug, textbooks and where relevant,
expert opinion. We cannot be held responsible for any errors
you make in administering drugs mentioned on this page, nor
for use of any erroneous information contained on this
page. |
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