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Eplerenone
API |
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Haorui supplies high quality Eplerenone API produced by our
GMP facility that has been successfully inspected by the
FDA.
We offer
competitive prices and support our products with reliable technical and
regulatory services. Eplerenone API is available from R&D to
commercial quantities. Please contact us for more details. |
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The following
information is provided for general information purposes
ONLY. |
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What is
Eplerenone? |
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Eplerenone is used alone or in combination
with other medications to treat high blood pressure.
Eplerenone is in a class of medications called
mineralocorticoid receptor antagonists. It works by blocking
the action of aldosterone, a natural substance in the body
that raises blood pressure. |
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What is
Eplerenone used for? |
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Eplerenone blocks the actions of the hormone
aldosterone in the body. Aldosterone is important for the
regulation of blood pressure |
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Eplerenone
is used to lower high blood pressure. Eplerenone is also
used in the treatment of congestive heart failure following
a heart attack. |
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Eplerenone Drug Interaction |
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Do not take eplerenone without first talking
to your doctor if you are taking any of the following drugs:
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a potassium supplement such as K-Dur, Klor-Con,
and others; |
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a salt substitute that contains potassium;
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a potassium-sparing diuretic (water pill)
such as triamterene, spironolactone, or amiloride;
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an angiotensin converting enzyme (ACE)
inhibitor such as benazepril, captopril, enalapril,
fosinopril, lisinopril, moexipril, perindopril, quinapril,
ramipril, or trandolapril; |
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an angiotensin II receptor inhibitor such
as candesartan, eprosartan, irbesartan, losartan,
olmesartan, telmisartan, or valsartan; |
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fluconazole, ketoconazole, or itraconazole;
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verapamil; |
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erythromycin; |
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lithium; |
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nefazodone |
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a protease inhibitor such as amprenavir,
ritonavir, nelfinavir, saquinavir, or indinavi; or
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delavirdine. |
You may not be able to take eplerenone, or
you may require a dosage adjustment or special monitoring
during treatment if you are taking any of the medicines
listed above.
Drugs other than those listed here may also
interact with eplerenone or affect your condition. Talk to
your doctor or pharmacist before taking any prescription or
over-the-counter medicines, including vitamins, minerals,
and herbal products. |
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Precautions Before Using Eplerenone |
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Before taking eplerenone,
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tell your doctor and pharmacist if you are allergic to
eplerenone or any other medications. |
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do not take eplerenone if you are taking amiloride,
amiloride and hydrochlorothiazide, itraconazole,
ketoconazole, potassium supplements, spironolactone,
spironolactone and hydrochlorothiazide, triamterene, or
triamterene and hydrochlorothiazide. |
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tell your doctor and pharmacist what other prescription
and nonprescription medications, vitamins, and nutritional
supplements you are taking. Be sure to mention any of the
following: angiotensin converting enzyme (ACE) inhibitors
such as benazepril, captopril, enalapril, fosinopril,
lisinopril, and quinapril; angiotensin II receptor
antagonists such as eprosartan, irbesartan, losartan,
olmesartan, and valsartan; aspirin and other nonsteroidal
anti-inflammatory medications such as ibuprofen and
naproxen; cimetidine; clarithromycin; danazol; delavirdine;
diltiazem; erythromycin; fluconazole; fluoxetine;
fluvoxamine; HIV protease inhibitors such as indinavir,
ritonavir, and saquinavir; isoniazid; lithium,
metronidazole; nefazodone; troleandomycin; verapamil; and
zafirlukast. Your doctor may need to change the doses of
your medications or monitor you carefully for side
effects. |
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tell your doctor what herbal products you are taking,
especially St. John' wort. |
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tell your doctor if you have or have ever had high blood
levels of potassium, diabetes, gout, or liver or kidney
disease. |
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tell your doctor if you are pregnant, plan to become
pregnant, or are breast-feeding. If you become pregnant
while taking eplerenone, call your doctor.
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Eplerenone side effects |
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Eplerenone may cause side effects. Tell your
doctor if any of these symptoms are severe or do not go
away:
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headache |
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dizziness |
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diarrhea |
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stomach pain |
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cough |
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excessive tiredness |
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flu-like symptoms |
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breast enlargement or tenderness |
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abnormal vaginal bleeding |
Some side effects can be serious. The
following symptoms are uncommon, but if you experience any
of them, call your doctor immediately:
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chest pain |
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tingling in arms and legs |
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loss of muscle tone |
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weakness or heaviness in legs |
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confusion |
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lack of energy |
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cold, gray skin |
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irregular heartbeat |
Eplerenone may cause other side effects. Call
your doctor if you have any unusual problems while taking
this medication. |
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What
should you do if you miss a dose of Eplerenone? |
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Take the missed dose as soon as you remember
it. However, if it is almost time for the next dose, skip
the missed dose and continue your regular dosing schedule.
Do not take a double dose to make up for a missed one. |
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Overdose
Eplerenone |
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Seek emergency medical attention if an
overdose is suspected.
Symptoms of an eplerenone overdose may
include vomiting, tremors, drowsiness and seizures. |
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Eplerenone Storage |
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Keep this medication in the container it came
in, tightly closed, and out of reach of children. Store it
at room temperature and away from excess heat and moisture
(not in the bathroom). Throw away any medication that is
outdated or no longer needed. Talk to your pharmacist about
the proper disposal of your medication. |
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Disclaimer:
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Information on this page is provided for general information
purposes. You should not make a clinical treatment decision
based on information contained in this page without
consulting other references including the package insert of
the drug, textbooks and where relevant, expert opinion. We
cannot be held responsible for any errors you make in
administering drugs mentioned on this page, nor for use of
any erroneous information contained on this page.
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