Desogestrel API

Haorui supplies high quality Desogestrel API produced by our GMP facility that has been successfully inspected by the FDA. We offer competitive prices and support our products with reliable technical and regulatory services.  Desogestrel API is available from R&D to commercial quantities. Please contact us for more details.

  The following information is provided for general information purposes ONLY.

 

What is Desogestrel?
Desogestrel is a molecule used in hormonal contraceptives. Third generation pills have been shown to resolve or to reduce acne and hirsutism. They are suitable for use in patients with diabetes or lipid disorders because they have minimal impact on blood glucose levels and the lipid profile. Their dosage is lower than other oral contraceptives.
How does Desogestrel work?
Desogestrel contains a hormone which is similar to the hormone progesterone that is produced by the body. It is used to prevent women from becoming pregnant. It works by preventing the release of eggs from the ovary and by increasing the thickness of vaginal fluid which can stop a sperm from reaching an egg.
Who should not use Desogestrel?
You should not use Desogestrel if : Known or suspected pregnancy. Active venous thromboembolic disorder. Presence or history of severe hepatic disease as long as liver function values have not returned to normal. Known or suspected sex-steroid sensitive malignancies. Undiagnosed vaginal bleeding. Hypersensitivity to the active substance or to any of the excipients.
How should I use Desogestrel?
Hormonal contraceptives will only prevent a pregnancy if they are taken regularly. It is important you take this medicine at the same time each day. When you first start to take Desogestrel you may need to take extra contraceptive precautions until it starts to work. You may also need to take extra contraceptive precautions in certain situations. These situations include missing a dose by more than 12 hours or vomiting within three to four hours of taking Desogestrel. Ask your prescriber, family planning nurse or read the patient information leaflet that comes with your medicine for more information about when to take additional contraceptive precautions. Other information about Desogestrel: for information about when you should start to take this medicine you should ask your prescriber, pharmacist or read the patient information leaflet that comes with your medicine you should start a new pack the day after you finish the current one. Do not have a break between packs
What happens if I miss a Desogestrel dose?
Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. You may also need to take extra contraceptive precautions.
What happens if I overdose?
There have been no reports of serious deleterious effects from overdose. Symptoms that may occur in this case are nausea, vomiting and, in young girls, slight vaginal bleeding. There are no antidotes and further treatment should be symptomatic.
What should I avoid while using Desogestrel?
Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you: are aged over 44 years are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine are immobile are pregnant or think you may be pregnant have breast cancer, liver cancer or any cancers that are sensitive to hormones have diabetes have galactose intolerance have glucose-galactose malabsorption problems have high blood pressure which is not well controlled have Lapp lactase deficiency have or have had chloasma have or have had liver problems have or have had thromboembolic problems have vaginal bleeding and the cause of the bleeding is not known
What are the possible side effects of Desogestrel?
Common: Between 1% and 10% of people who take Desogestrel acne breast pain decreased libido headaches menstrual problems including irregular menstrual periods or amenorrhoea. You should seek medical advice if you have been taking Desogestrel regularly and you bleed more often, if your periods are irregular or if you do not have a menstrual period mood changes nausea weight gain Uncommon: Between 0.1% and 1% of people who take Desogestrel hair loss heavy or painful menstrual periods infection of the vagina intolerance to contact lenses ovarian cyst tiredness vomiting - you may need to take extra contraceptive precautions if you vomit within three to four hours of taking Desogestrel Rare: Between 0.01% and 0.1% of people who take Desogestrel skin problems including skin rashes, erythema or urticaria The frequency of these side-effects is unknown angioedema blood problems discharge from the breast ectopic pregnancy - seek medical advice if you have stomach pain or amenorrhoea gallstones hearing loss infections liver problems including jaundice or itching lupus or lupus-like problem porphyria or porphyria-like reaction raised blood pressure - seek medical advice if this occurs worsening of chorea The frequency of these side-effects is unknown and has been reported in women who have taken combined oestrogen and progestogen contraceptives chloasma - if you are prone to having chloasma, you should avoid exposure to the sun or ultraviolet light while taking Desogestrel hormone sensitive cancers such as liver or breast cancer may affect the results for certain tests thromboembolic problems such as deep vein thrombosis or pulmonary embolism - these problems may return in women who have had them before. Hormonal contraceptives may also increase the chances of developing breast cancer. You and your prescriber will need to weigh up the benefits and risks of taking Desogestrel before you start to take it. Women who take Desogestrel need to regularly examine their breasts for any changes or lumps.
What other drugs will affect Desogestrel?
The following medicines may interact with Desogestrel: carbamazepine charcoal ciclosporin felbamate griseofulvin nelfinavir oxcarbazepine phenobarbital phenytoin primidone rifabutin rifampicin ritonavir topiramate The following types of medicine may interact with Desogestrel: barbiturates hydantoins
Where can I get more information?
If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Desogestrel Storage
Desogestrel does not require any special storage conditions.
Nursing Mothers use of Desogestrel
Desogestrel passes into breast milk. If you take this medicine while breastfeeding, your baby may need some extra monitoring
Pregnancy and use of Desogestrel
do not take Desogestrel during pregnancy your prescriber will only start your treatment with Desogestrel once they are certain that you are not pregnant.
Disclaimer:
Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.