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1 |
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|
| Conditions: |
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Head and Neck Cancer;
Lung Cancer |
| Intervention: |
|
Drug: Ethyol (Amifostine) |
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2 |
|
|
| Condition: |
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Colorectal Cancer |
| Intervention: |
|
Drug: Amifostine |
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3 |
|
|
| Condition: |
|
Head and Neck Cancer |
| Interventions: |
|
Drug: Amifostine;
Procedure: Intensity- Modulated Radiation Therapy |
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4 |
|
|
| Conditions: |
|
Lymphoma;
Hodgkin's Disease;
Non-Hodgkin's Lymphoma |
| Interventions: |
|
Drug: Amifostine;
Radiation: Radiation Therapy |
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|
5 |
|
|
| Conditions: |
|
Leukemia;
Acute Myeloid Leukemia |
| Intervention: |
|
Drug: Ethyol |
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6 |
|
|
| Conditions: |
|
Head and Neck Cancer;
Lung Cancer; Lymphoma |
| Intervention: |
|
Drug: Amifostine administered subcutaneously |
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|
7 |
|
|
| Condition: |
|
Head and Neck Cancer. |
| Interventions: |
|
Drug: Amifostine;
Drug: Carboplatin; Drug: Taxol;
Device: Radiotherapy |
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|
8 |
|
|
| Condition: |
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Cancer |
| Intervention: |
|
Procedure: Blood and
salivary sampling of amifostine |
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9 |
|
|
| Condition: |
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Malignant Pleural Mesothelioma |
| Interventions: |
|
Procedure: Extrapleural pneumonectomy (EPP);
Drug: cisplatin; Drug: gemcitabine;
Drug: amifostine;
Drug: sodium thiosulfate |
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10 |
|
|
| Conditions: |
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Carcinoma of Unknown Primary;
Head and Neck Cancer; Quality of Life |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: fluorouracil;
Drug: paclitaxel;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: quality-of-life assessment;
Procedure: radiation therapy |
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11 |
|
|
| Conditions: |
|
Esophagitis;
Pneumonitis;
Non-Small Cell Lung Carcinoma |
| Intervention: |
|
Drug: Amifostine |
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12 |
|
|
| Condition: |
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Myelodysplastic Syndromes |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: azacitidine;
Procedure: chemoprotection;
Procedure: chemotherapy |
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|
13 |
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|
| Conditions: |
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Drug Toxicity;
Multiple Myeloma and Plasma Cell Neoplasm |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: clarithromycin;
Drug: dexamethasone; Drug: melphalan;
Drug: thalidomide;
Procedure: antiangiogenesis therapy;
Procedure: bone marrow ablation with stem cell
support; Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: high-dose chemotherapy;
Procedure: management of therapy complications;
Procedure: non-specific immune-modulator therapy;
Procedure: peripheral blood stem cell
transplantation |
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14 |
|
|
| Condition: |
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Myelodysplastic Syndromes |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: chemotherapy |
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|
15 |
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|
| Conditions: |
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Leukemia;
Myelodysplastic Syndromes |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: topotecan hydrochloride;
Procedure: chemoprotection;
Procedure: chemotherapy |
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16 |
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|
| Conditions: |
|
Drug Toxicity;
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: chemoprotection |
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|
17 |
|
|
| Conditions: |
|
Drug Toxicity;
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin;
Drug: gemcitabine hydrochloride;
Procedure: chemoprotection;
Procedure: chemotherapy |
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18 |
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|
| Condition: |
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Lymphoma |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: cytarabine;
Drug: dexamethasone;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: hematologic toxicity attenuation;
Procedure: peripheral blood stem cell
transplantation |
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19 |
|
|
| Conditions: |
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Gestational Trophoblastic Tumor;
Neurotoxicity;
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: neurotoxicity attenuation |
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20 |
|
|
| Conditions: |
|
Drug Toxicity;
Lung Cancer;
Oral Complications of Cancer and Cancer Therapy;
Quality of Life; Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: carboplatin; Drug: filgrastim;
Drug: paclitaxel;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: colony-stimulating factor therapy;
Procedure: quality-of-life assessment;
Procedure: radiation therapy;
Procedure: radioprotection |
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21 |
|
|
| Condition: |
|
Myelodysplastic Syndromes |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: chemoprotection |
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22 |
|
|
| Conditions: |
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Chemotherapeutic Agent Toxicity;
Dysphagia; Head and Neck Cancer;
Mucositis; Radiation Toxicity;
Xerostomia |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: carboplatin; Drug: paclitaxel;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: cytogenetic analysis;
Procedure: diagnostic procedure;
Procedure: exercise intervention;
Procedure: fatigue assessment and management;
Procedure: intensity-modulated radiation therapy;
Procedure: laboratory biomarker analysis;
Procedure: liquid chromatography;
Procedure: management of therapy complications;
Procedure: mass spectrometry;
Procedure: nutritional support;
Procedure: proteomic profiling;
Procedure: quality-of-life assessment;
Procedure: radioprotection;
Procedure: therapeutic dietary intervention |
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23 |
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| Conditions: |
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Prostate Cancer;
Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: radiation therapy;
Procedure: radioprotection |
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24 |
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|
| Conditions: |
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Ovarian Cancer;
Quality of Life |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: chemoprotection;
Procedure: neurotoxicity attenuation;
Procedure: quality-of-life assessment |
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25 |
|
|
| Conditions: |
|
Myelodysplastic Syndromes;
Myelodysplastic/Myeloproliferative Diseases |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: chemotherapy |
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|
26 |
|
|
| Conditions: |
|
Breast Cancer;
Lung Cancer; Neurotoxicity;
Ovarian Cancer; Prostate Cancer;
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: management of therapy complications;
Procedure: neurotoxicity attenuation |
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27 |
|
|
| Conditions: |
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Anemia;
Myelodysplastic Syndromes |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: epoetin alfa;
Procedure: colony-stimulating factor therapy;
Procedure: hematologic toxicity attenuation |
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28 |
|
|
| Conditions: |
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Leukemia;
Lymphoma;
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
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Drug: amifostine trihydrate;
Drug: carboplatin; Drug: filgrastim;
Drug: paclitaxel;
Procedure: chemotherapy;
Procedure: colony-stimulating factor therapy;
Procedure: hematologic toxicity attenuation;
Procedure: neurotoxicity attenuation |
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29 |
|
|
| Conditions: |
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Drug Toxicity;
Leukemia |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cytarabine; Drug: idarubicin;
Procedure: cardiotoxicity attenuation;
Procedure: chemotherapy; Procedure: neurotoxicity attenuation |
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30 |
|
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| Conditions: |
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Bladder Cancer;
Brain and Central Nervous System Tumors;
Carcinoma of Unknown Primary;
Extragonadal Germ Cell Tumor;
Head and Neck Cancer; Kidney Cancer;
Lung Cancer; Ovarian Cancer;
Sarcoma; Testicular Germ Cell Tumor;
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: carboplatin; Drug: etoposide;
Drug: filgrastim; Drug: ifosfamide;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: colony-stimulating factor therapy;
Procedure: peripheral blood stem cell
transplantation |
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31 |
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|
| Conditions: |
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Cervical Cancer;
Endometrial Cancer;
Fallopian Tube Cancer; Neurotoxicity;
Ovarian Cancer;
Peritoneal Cavity Cancer; Sarcoma |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: paclitaxel;
Procedure: chemotherapy;
Procedure: management of therapy complications;
Procedure: neurotoxicity attenuation |
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32 |
|
|
| Conditions: |
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Drug Toxicity;
Head and Neck Cancer; Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: paclitaxel;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: radiation therapy;
Procedure: radioprotection |
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33 |
|
|
| Conditions: |
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Chronic Myeloproliferative Disorders;
Drug Toxicity; Leukemia;
Lymphoma;
Multiple Myeloma and Plasma Cell Neoplasm;
Myelodysplastic Syndromes;
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: carboplatin;
Drug: cyclophosphamide;
Drug: sargramostim;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: colony-stimulating factor therapy |
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34 |
|
|
| Conditions: |
|
Breast Cancer;
Drug Toxicity; Lung Cancer;
Lymphoma; Ovarian Cancer;
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: cyclophosphamide;
Drug: etoposide; Drug: sargramostim;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: colony-stimulating factor therapy |
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35 |
|
|
| Conditions: |
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Drug Toxicity;
Lung Cancer; Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: etoposide;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: radiation therapy;
Procedure: radioprotection |
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36 |
|
|
| Conditions: |
|
Drug Toxicity;
Multiple Myeloma and Plasma Cell Neoplasm |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: filgrastim; Drug: melphalan;
Procedure: bone marrow ablation with stem cell
support; Procedure: chemoprotection;
Procedure: colony-stimulating factor therapy;
Procedure: high-dose chemotherapy;
Procedure: peripheral blood stem cell
transplantation |
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37 |
|
|
| Condition: |
|
Unspecified Adult Solid Tumor, Protocol Specific |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: paclitaxel;
Procedure: chemoprotection;
Procedure: chemotherapy |
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|
38 |
|
|
| Conditions: |
|
Drug Toxicity;
Head and Neck Cancer;
Oral Complications of Cancer and Cancer Therapy;
Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: management of therapy complications;
Procedure: radiation therapy;
Procedure: radioprotection |
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|
39 |
|
|
| Conditions: |
|
Bladder Cancer;
Drug Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: gemcitabine hydrochloride;
Procedure: adjuvant therapy; Procedure: chemoprotection;
Procedure: chemotherapy |
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40 |
|
|
| Conditions: |
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Brain and Central Nervous System Tumors;
Childhood Germ Cell Tumor; Chordoma;
Drug Toxicity;
Extragonadal Germ Cell Tumor;
Kidney Cancer; Liver Cancer;
Neuroblastoma; Ovarian Cancer;
Retinoblastoma; Sarcoma;
Testicular Germ Cell Tumor |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: busulfan; Drug: filgrastim;
Drug: melphalan; Drug: thiotepa;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: colony-stimulating factor therapy;
Procedure: peripheral blood stem cell
transplantation |
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41 |
|
|
| Conditions: |
|
Drug Toxicity;
Lung Cancer |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: docetaxel;
Procedure: chemoprotection;
Procedure: chemotherapy |
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|
42 |
|
|
| Conditions: |
|
Childhood Germ Cell Tumor;
Drug Toxicity;
Extragonadal Germ Cell Tumor;
Ovarian Cancer |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: bleomycin; Drug: cisplatin;
Drug: etoposide;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: conventional surgery |
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43 |
|
|
| Conditions: |
|
Prostate Cancer;
Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Procedure: radiation therapy;
Procedure: radioprotection |
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|
44 |
|
|
| Conditions: |
|
Drug Toxicity;
Head and Neck Cancer;
Oral Complications of Cancer and Cancer Therapy;
Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: carboplatin; Drug: cisplatin;
Drug: paclitaxel;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: radiation therapy;
Procedure: radioprotection |
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|
45 |
|
|
| Condition: |
|
Breast Cancer |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cyclophosphamide;
Drug: doxorubicin hydrochloride; Drug: filgrastim;
Drug: paclitaxel; Procedure: chemoprotection;
Procedure: chemotherapy; Procedure:
peripheral blood stem cell transplantation |
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|
46 |
|
|
| Conditions: |
|
Drug Toxicity;
Lung Cancer |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: carboplatin; Drug: paclitaxel;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: radiation therapy |
| |
|
47 |
|
|
| Conditions: |
|
Cervical Cancer;
Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Procedure: brachytherapy;
Procedure: chemotherapy;
Procedure: radiation therapy;
Procedure: radioprotection |
| |
|
48 |
|
|
| Conditions: |
|
Drug Toxicity;
Head and Neck Cancer; Oral Complications
of Chemotherapy and Head/Neck Radiation;
Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: carboplatin; Drug: paclitaxel;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: management of therapy complications;
Procedure: radiation therapy;
Procedure: radioprotection |
| |
|
49 |
|
|
| Conditions: |
|
Drug Toxicity;
Lung Cancer; Radiation Toxicity |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cisplatin; Drug: etoposide;
Procedure: chemoprotection;
Procedure: chemotherapy;
Procedure: radiation therapy;
Procedure: radioprotection |
| |
|
50 |
|
|
| Conditions: |
|
Drug Toxicity;
Leukemia; Myelodysplastic Syndromes;
Neutropenia |
| Interventions: |
|
Drug: amifostine trihydrate;
Drug: cytarabine; Drug: mitoxantrone hydrochloride;
Procedure: chemotherapy; Procedure: hematologic toxicity attenuation |